Knee osteoarthritis is a common degenerative joint disease that can lead to chronic pain and limited mobility. Treatments like Arthrosamid and Hyaluronic Acid (Ostenil) knee injections have emerged as advanced therapeutic options for managing this condition. While both are injectable solutions, they differ in composition, how they work, and their long-term effectiveness. Understanding these differences can help patients and healthcare providers choose the most suitable treatment for knee osteoarthritis.
What are they?: Arthrosamid vs. Hyaluronic Acid
Arthrosamid is a modern injectable hydrogel primarily made from polyacrylamide, a synthetic polymer. Unlike other treatments, its non-biodegradable structure means it remains in the joint, creating a stable cushion that integrates into the knee’s synovial tissue. It acts as a scaffold of sorts. This allows Arthrosamid to provide long-term cushioning and reduce mechanical stress on the joint.
Hyaluronic Acid (HA) is a naturally occurring substance found in the body’s joint fluid. The injectable form is either sourced from animals or produced synthetically. HA temporarily supplements the natural hyaluronic acid that decreases in osteoarthritic joints, improving joint lubrication. However, because it is biodegradable, it is gradually absorbed by the body, requiring repeated injections for continued relief.
How do they work?
Arthrosamid works by enhancing the joint’s viscoelastic properties. Once injected, the hydrogel integrates with the synovial membrane, forming a protective layer that reduces joint stress and offers sustained pain relief. Arthrosamid has been shown to maintain joint space, which may slow down osteoarthritis progression, making it effective for several years.
Hyaluronic Acid, on the other hand, restores the viscosity of the synovial fluid. In osteoarthritic joints, HA levels decrease, causing increased friction and pain. By injecting HA, the treatment helps to lubricate the joint, leading to temporary pain relief and improved mobility. However, its effects are usually short-lived, lasting between 6 to 18 months, depending on the patient.
How effective are they?
Clinical studies show that Arthrosamid offers long-lasting pain relief, with benefits often extending up to three years or more. This longevity is due to its durable integration into the joint, providing mechanical support and cushioning even after the initial injection.
Hyaluronic Acid injections, while effective, offer a shorter duration of relief, typically between 6 and 18 months. Patients’ responses to HA can vary, and repeat injections are necessary to maintain its benefits. Despite this, HA remains a popular treatment, especially for those in the early stages of osteoarthritis.
Which Treatment is Right for You?
Hyaluronic Acid is generally recommended for patients with mild to moderate knee osteoarthritis. It’s best suited for those with earlier-stage osteoarthritis who prefer a treatment with a long-standing safety profile and can tolerate repeated injections. It’s also better for those on a budget.
Arthrosamid is a better option for those with more advanced osteoarthritis, particularly those seeking long-term relief. It’s ideal for patients with significant joint space narrowing who have not responded well to other treatments or are looking to delay knee replacement surgery.
Chat to Gill or the physio team if you wish to find out more, or discuss your suitability for these treatments.